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In 2014, the Center for Genome Innovation (CGI) was established within the Institute for Systems Genomics, under the direction of Rachel O’Neill, Professor of Molecular and Cell Biology.  The mission of the CGI is to provide state-of-the-art expertise in genome technologies while facilitating genomics research for faculty and students across the University of Connecticut campuses.

Located on both the Storrs and Farmington campuses, the CGI’s infrastructure serves as a nexus for computational biology support and maintains a diverse portfolio of genomics instrumentation from microfluidics, arrays and next generation sequencing. Support for these technologies are in the form of experienced user access, hands-on assistance, training and/or consultation through the CGI.

The CGI offers a variety of laboratory training opportunities as well as sample QC, NextGen library preparation/sequencing and genotyping services. These services are available to UConn-affiliated researchers across all campuses and range from single run instrument access through full-service NextGen library preparation and sequencing.  All services are also available to external users and for-profit companies.

The CGI also offers laboratory-based workshops for a variety of NextGen sequencing applications, including RNA-Seq, amplicon sequencing and ChIP-Seq.  Free consultations are also available for experimental design, budgeting and troubleshooting.

Click Here for an Update from the CGI During COVID-19



The CGI has expanded its sequencing portfolio with the addition of the Illumina NovaSeq 6000

Illumina NovaSeq 6000This sequencer offers users scalable throughput and significant cost savings over currently available in-house sequencers.  Details of instrument specifications can be found here.

The NovaSeq 6000 has the ability to sequence 1 or 2 flow cells at a time, with 13 different throughput and cycle configurations (in addition to lane sharing options).  Compared to the NextSeq 550, the NovaSeq 6000’s SP configuration doubles the throughput of a standard NextSeq High Output 150 cycle sequencing kit (400M versus 800M clusters) and offers increased read lengths by 33% for only $91 more!  And now, with the launch of version 1.5 sequencing reagents, users will now be able to sequence the human genome for as little as $700!